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International Conference and Expo on Dermatopathology and Skin Care

Toronto, Canada

Jeung-Hoon Lee

Chungnam National University, Daejeon, Korea

Title: Prurigo pigmentosa after a low-carbohydrate diet


Biography: Jeung-Hoon Lee


Prurigo pigmentosa (PP) is a severe pruritic skin disease in young adults with recurrent eruptions of pruritic erythematous macules and papules.  The etiology of prurigo pigmentosa is not well known but many studies have focused on dietary modification and ketosis. A 24-year-old female presented with pruritic erythematous plaques on her upper chest which appeared since 2 months ago. The patient undertook a low-carbohydrate high-fat diet one month before the eruption of the skin lesions. Histopathological examination showed intracorneal microabscess, necrotic keratinocytes, exocytosis with spongiosis, vacuolar degeneration of basal cells, and superficial perivascular mononuclear cell infiltration with neutrophils. The rash improved significantly with diet modification and oral minocycline medication. Here, we report a case of prurigo pigmentosa associated with a low-carbohydrate diet.